Imidazole: Having Versatile Biological Activities
Imidazole: Having Versatile Biological Activities
Blog Article
Imidazoles have occupied a unique position in heterocyclic chemistry, and its derivatives have attracted considerable interests in recent years for their Outdoor Grills versatile properties in chemistry and pharmacology.Imidazole is nitrogen-containing heterocyclic ring which possesses biological and pharmaceutical importance.Thus, imidazole compounds have been an interesting source for researchers for more than a century.The imidazole ring is a constituent of several important natural products, including purine, histamine, histidine, and nucleic acid.
Being a polar and ionisable aromatic compound, it improves pharmacokinetic characteristics of lead molecules and thus is used as a remedy to optimize solubility and bioavailability parameters of proposed poorly soluble lead molecules.There are several methods used for the synthesis of imidazole-containing compounds, and also their various structure reactions offer enormous scope in the field of medicinal chemistry.The imidazole derivatives possess extensive spectrum of biological activities such as antibacterial, Fiber/Bran Supplements anticancer, antitubercular, antifungal, analgesic, and anti-HIV activities.This paper aims to review the biological activities of imidazole during the past years.